Therapeutic Dilemma of Bacterial Prostatitis Syndrome

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Sebha University
Objective: to investigate the aetiology and treatment of bacterial prostatitis syndrome in south Libya. Setting: El-Najah Polyclinic, Sebha, South Libya. Materials and Methods: This prospective study was conducted in El-Najah Polyclinic in the period from October 2003 to September 2006. The premassage and postmassage testing technique of prostatitis was employed to investigate patients with the clinical diagnosis of prostatitis syndrome. Collected specimens were cultured in Muller Hinton agar media for quantitative culture and sensitivity testing. Results: Out of a total of 250 patients with prostatitis syndrome, 88(35.2%) patients proved to have bacterial prostatitis. Escherichia coli (38.6%) was the commonest offending organism followed by Staphylococcus aureus (37.5%) and Pseudomonas auerginosa (11.3%). Gentamicin, Nitrofurantoin and Amoxycillin were the most effective agents against E. coli and Staphylococci. The vast majority of prostatic bacterial isolates were resistant to Erythromycin and Trimethoprim. Such pattern of resistance to these drugs described as the most effective agents for the treatment of bacterial prostatitis, indicates that treatment of bacterial prostatitis syndrome would pose a problem in this area. Trimethoprim-sulphamethoxazole and new quinolones were reported to have the best-confirmed cure rates in recent prospective bacterial protatitis studies and need to be investigated in a future study.