Selective Laser Trabeculoplasty in Patients with Medically Uncontrolled Open Angle Glaucoma

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Sebha University
AIMS: To assess the effectiveness of selective laser trabeculoplasty (SLT, a Q switched, frequency doubled Nd:YAG laser,  = 532 nm) in lowering the intraocular pressure (IOP) in patients with medically uncontrolled open angle glaucoma attending the glaucoma clinic in the Great river eye hospital, Benghazi . Methods: A prospective clinical trial was designed. 25 Patients and 30 eyes with open Angle Glaucoma were set to treatment with SLT and were evaluated at 1 hour, 24 hours, 1 week, 1 month and 3 months post-laser. Results: There were 30 eyes in the SLT treatment group, the mean IOP at baseline, 1 hour, 1 week, and 3 months was 24.56 (SD 3.15), 27.6 (3.85), 27.0 (3.7), 23.8 (3,1), 20.8 (3.0), and 19.7 (2.59) mm Hg, respectively. There was a anterior chamber reaction, 1 hour after SLT in 18 eyes (p< 0.01) and one patient with hyphema. Conclusion: SLT appears to be an important and effective method in lowering intraocular pressures in patients with open angle glaucoma. There is a slightly marked post-laser anterior chamber reaction at 1 hour after SLT. These results are encouraging and suggest that SLT should be investigated further as an IOP lowering treatment in open angle glaucoma. These results need to be confirmed with a larger sample size.