Ali Farag Hawad, Ibrahim Ali Al Tayyar,2018-02-202018-02-202013https://repository.sebhau.edu.ly/handle/1/626Staphylococcus aureus is environmental organism commonly found and most of them are opportunistic pathogens that colonized in human bodies cause various human disease. To determine the prevalence and antibiotic susceptibility pattern for multidrug and non-multidrug methicillin/oxacillin resistant S. aureus (MRSA) 133 S. aureus strains, isolated from different clinical specimens submitted to Department of Microbiology, Saad Speciality Hospital Laboratory, Saudi Arabia between November 2008 and September 2010. The percentage of MRSA and MDR were 39.1 % and 54.9 %, respectively. While the remaining strains were considered as Oxacillin sensitive S. aureus (OSSA) represented (60.9 %) more than half percentage of total isolated S. aureus. From 14 sample source of clinical specimens, the most common source of all isolated species combined was abscesses 62 (46.5%) isolate, followed by nasal swab 19 (14.3%) isolate, respiratory sample 14 (10.5%) isolate, wound 13 (10%) isolate, while the other teen source combined 25 (18.7%) isolate of all isolated S. aureus. S. aureus strains in general showed highly sensitive percentage to Vancomycin (100%), Linozolid (100%), Rifampin (98.5%), Nitrofurantin (97.7%) and Trimethoprim-Sulfamethoxazole (93.2). Moreover, the lowest sensitive rate was observed with Penicillin (3%), Ampicillin (4.5%), Ceftriaxon (22%).enArticle